Tooth dentin regeneration and its clinical application

Bae,  Hyun Sook; Park,  Joo-Cheol

J Korean Dent Assoc > Volume 55(5); 2017 > Article

The Journal of The Korean Dental Association 2017;55(5):352-357.
Published online May 31, 2017.

치아 상아질의 재생과 그 임상적 활용

배현숙¹, 박주철²

^¹남서울대학교 치위생학과
^²서울대학교 치의학대학원 구강조직.발생생물학교실

Tooth dentin regeneration and its clinical application

Hyun Sook Bae¹, Joo-Cheol Park²

¹Department of Dental Hygiene, Namseoul University
²Department Oral Histology.Developmental Biology, School of Dentistry, Seoul National University

Abstract

Teeth are made up of three hard tissues, enamel, dentin, and cementum. The dental pulp is the only non-mineralized connective tooth tissue that is surrounded by dentin. The dentin-pulp complex is able to respond to injury by producing hard tissue deposition. However, dentin is considered one of the most difficult tissues to regenerate because of its unique anatomic and physiologic nature. Recently, advances in understanding the applicability of bio-active dentin regenerating proteins are emerging with the development of biological-based therapies using bio-active materials. Dentin defects were regenerated by the deposition of tubular physiologic dentin after application of the bio-active protein in a beagle dog model. Therefore, the bio-active protein may be able to serve as a novel dentin regenerating material and improve symptoms of dentin hypersensitivity.

Key Words: Tubular dentin;Odontoblast;Regeneration;Tooth hypersensitivity;