Current Advancement of Oral Cancer Research and its Clinical Implications

Kwon,  Tae-Geon; Kim,  Chin-Soo

J Korean Dent Assoc > Volume 48(8); 2010 > Article

The Journal of The Korean Dental Association 2010;48(8):576-586.
Published online August 31, 2010.

구강암의 연구동향 및 임상적 의의

권대근¹, 김진수²

^¹경북대학교 치의학전문대학원 구강악안면외과학교실
^²경북대학교 치의학전문대학원 구강악안면외과학교실

Current Advancement of Oral Cancer Research and its Clinical Implications

Tae-Geon Kwon¹, Chin-Soo Kim²

¹Department of Oral & Maxillofacial Surgery, School of Dentistry, Kyungpook National University
²Department of Oral & Maxillofacial Surgery, School of Dentistry, Kyungpook National University

Abstract

Recent advancement in molocular biology enhanced further understanding of the carcinogenesis of oral cancer and its relation with various genetic backgrounds. Familial risk factors includes similar habits of the family and polymorphic variations of the genes. Recently, human papilloma virus has been suggested to be linked with oral cancer progression. Enhancement of understanding of the damage or alteration in molecular pathway in various cellular response of oral cancer progression would lead the targeted therapy or precise early diagnosis of the oral cancer.

Key Words: oral cancer;research;molecular biology;clinical implication;