| 롱코비드 시대 구강 건강 관리 : 코로나19와 치주 질환 연관성을 중심으로 |
정재석1,3 
, 허석모2,3
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1전북대학교 의과대학 호흡기내과학교실
2전북대학교 치과대학 치주과학교실
3전북대학교 임상의학연구소-전북대학교병원 의생명연구원 |
| Oral health care in the long COVID era : Focusing on the relationship between COVID-19 and periodontal disease |
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Jae Seok Jeong1,3
, Seok-Mo Heo2,3
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1Department of Internal Medicine, Research Center for Pulmonary Disorders, Jeonbuk National University Medical School, Jeonju, South Korea
2Department of Periodontology, School of Dentistry, Jeonbuk National University, Jeonju, South Korea
3Research Institute of Clinical Medicine of Jeonbuk National University, Jeonju, South Korea |
Correspondence:
Seok-Mo Heo, Tel: +82-63-250-2018, Fax: +82-63-250-2259,
Email: neoheo@jbnu.ac.kr
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Received: 2 June 2022 • Revised: 8 June 2022 • Accepted: 20 June 2022 |
| Abstract |
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The purpose of this study is to investigate the relationship between periodontal disease and coronavirus disease 2019 (COVID-19) as a respiratory disease, and to suggest its molecular biological mechanism. Oral bacteria and viruses can be aspirated into the respiratory tract and may cause respiratory diseases. The COVID-19 virus can inhabit, replicate and spread in the oral environment including dental plaque, saliva, and periodontal pockets. The COVID-19 virus can induce strong innate immunity and inflammatory responses by binding to the angiotensin-converting enzyme 2 receptors, which are abundantly present in the oral stratified epithelium in the oral cavity. The COVID-19 virus may activate inflammasome, one of inflammatory key factors in cell cytoplasm. In patients with periodontal disease, oral hygiene habits, professional oral cleaning, and plaque control management are effective for reducing the possibility of COVID-19 infection. This review is based on the evidences from COVID-19 related literature in the last two years. |
| Key Words:
long COVID; periodontal disease; COVID-19; inflammasome; oral hygiene |
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