법랑질 병소 회복율 평가를 위한 QLF 기술의 적용 |
김경민1, 구혜민2, 이은송3, 강시묵4, 5, 권호근6, 김백일7 |
1연세대학교 치과대학 예방치과학교실 2연세대학교 치과대학 예방치과학교실 3연세대학교 치과대학 예방치과학교실 4연세대학교 치과대학 예방치과학교실 5연세대학교 치과대학 예방치과학교실 6연세대학교 치과대학 예방치과학교실 7연세대학교 치과대학 예방치과학교실 |
Application of the QLF technology to monitor recovery rates of enamel caries lesions with human saliva |
Gyung-Min Kim1, Hye-Min Ku2, Eun-Song Lee3, Si-Mook Kang4, Elbert de Josselin de Jong5, Ho-Keun Kwon6, Baek-Il Kim7 |
1Department of Preventive dentistry & Public Oral Health, BK 21 PLUS Project, Yonsei University College of Dentistry 2Department of Preventive dentistry & Public Oral Health, BK 21 PLUS Project, Yonsei University College of Dentistry 3Department of Preventive dentistry & Public Oral Health, BK 21 PLUS Project, Yonsei University College of Dentistry 4Department of Preventive dentistry & Public Oral Health, BK 21 PLUS Project, Yonsei University College of Dentistry 5Department of Preventive dentistry & Public Oral Health, BK 21 PLUS Project, Yonsei University College of Dentistry 6Department of Preventive dentistry & Public Oral Health, BK 21 PLUS Project, Yonsei University College of Dentistry 7Department of Preventive dentistry & Public Oral Health, BK 21 PLUS Project, Yonsei University College of Dentistry |
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Abstract |
Purpose The aim of this in vitro study was to assess changes in remineralization by stimulated human saliva over a short period of 48 hours with quantitative light-induced fluorescence (QLF) technology. Materials and Methods: Bovine incisor surfaces were demineralized for 10 days. Two types of stimulated saliva were collected from 7 healthy persons. 24 hours after tooth brushing (Stimulated saliva group) and immediately after tooth brushing with 1,000 ppm NaF dentifrice (Dentifrice saliva group). The specimens were immersed in saliva and fluorescence images were obtained by QLF-digital (QLF-D biluminatorTM,) at 2, 4, 6, 12, 24, and 48 hours fluorescence loss (DeltaF%) of the lesions. A paired t-test was performed to assess fluorescence differences between before (DeltaF_baseline) and after (DeltaF_treatment;time) the remineralization process. Results: Before the remineralization, the mean DeltaF_baseline of the initial demineralized specimens was -18.42pm0.15 (%). In both groups, the DeltaF values obtained at baseline and after 2 hours were statistically significant (P < 0.001), indicating recovery of the lesions by approximately 40% after 2 hours. After 48 hours, remineralization rates were slightly higher (49%) for the stimulated saliva group than for the dentifrice saliva group (41%), but the difference was not statistically significant. Conclusions: With QLF minute degrees of remineralization by saliva can be measured in periods as short as 2 hours. Additionally no significantly higher effects of remineralization were observed in the dentifrice saliva group when compared to the stimulated saliva group. |
Key Words:
Remineralization;QLF;Incipient caries lesion; |
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