Pathogens and Their Antimicrobial Susceptibilities of Endodontic Infection in Type II Diabetes Mellitus Patients

Cho,  Ju-Yeon; Kim,  Sung-Kyo

doi:2016.54.5.356

J Korean Dent Assoc > Volume 54(5); 2016 > Article

The Journal of The Korean Dental Association 2016;54(5):356-364.
DOI: https://doi.org/10.22974/jkda.2016.54.5.004 Published online May 31, 2016.

제 2형 당뇨 환자의 근관 감염에서 나타난 병원균과 그 항생제 감수성

조주연¹, 김성교²

^¹계명대학교 의과대학 동산의료원 치과
^²경북대학교 치과대학병원 치과보존과

Pathogens and Their Antimicrobial Susceptibilities of Endodontic Infection in Type II Diabetes Mellitus Patients

Ju-Yeon Cho¹, Sung-Kyo Kim²

¹Department of Dentistry, Keimyeong University Dongsan Medical Center
²Department of Conservative Dentistry, Kyngpook National University Hospital

Abstract

Aim
The purpose of this study was to identify dominant pathogens and their antimicrobial susceptibilities of endodontic infection in type II diabetes mellitus (DM) patients to determine effective empirical antibiotics. Methodology: Pathogens from endodontic infection in six patients with DM and in six patients without DM were cultured, identified and their antimicrobial susceptibility was tested using Vitek2 systems (bioMacuteerieux, Marcy l' Etoile, France). The results were analyzed using Chi-square test and Fisher's exact test at P< 0.05 level. Results: Pathogens of opportunistic infection were dominant in DM patients (P=0.015). However, there was no significant difference of antimicrobial susceptibility between DM and non-DM patients. Relatively high percent (27%) of pathogens showed resistance to penicillin. Conclusions: More cautions should be paid to DM patients because they are prone to opportunistic infection. Penicillin is not effective in the control of endodontic infection.

Key Words: Diabetes mellitus;Pathogen;Endodontic;Infection;