Clinical effect of calcium chelating and deproteinizing agent containing dental conditioning gel on alleviation of periimplant mucosa inflammation

Yang,  Kwang-Heon; Lee,  Jue-Yeon; Jung,  Jin-Hyung; Shin,  Hyun-Seung; Cho,  In-Woo

J Korean Dent Assoc > Volume 53(9); 2015 > Article

The Journal of The Korean Dental Association 2015;53(9):618-627.
Published online September 30, 2015.

Clinical effect of calcium chelating and deproteinizing agent containing dental conditioning gel on alleviation of periimplant mucosa inflammation

Kwang-Heon Yang¹, Jue-Yeon Lee², Jin-Hyung Jung³, Hyun-Seung Shin⁴, In-Woo Cho⁵

¹Department of Periodontology, Dankook University of Dentistry
²Central Research Institute, Nano Intelligent Biomedical Engineering Corporation(NIBEC)
³Department of Periodontology, Dankook University of Dentistry
⁴Department of Periodontology, Dankook University of Dentistry
⁵Department of Periodontology, Dankook University of Dentistry

Abstract

Purpose
: The purpose of this clinical study was to evaluate the effect of chelating and deproteinizing agent containing dental conditioning gel on alleviation of peri-implant mucosa inflammation. Methods: 36 patients with functionally loaded implants for at least 1 year and have clinical signs of peri-implant mucositis were recruited. At baseline, all implants received subgingival prophylaxis with ultrasonic scaler. In the test group, patients were provided a chelating and deproteinizing agent dental conditioning gel (Clinplant(R)) and were given instructions to applicate it around the implants using an interdental brush for 2 weeks. Chlorhexidine and saline were provided to the positive control group and negative control group, respectively. The modified sulcus bleeding index (mSBI), modified plaque index (mPI), and probing pocket depth (PPD) were evaluated at baseline, 1 week, and 2 weeks. Results: In the Clinplant(R) and chlorhexidine group, mSBI (-0.81, -0.85 respectively; p<0.01), mPI (-0.46, -0.5 respectively; p<0.01), and PPD (-0.58, -0.48 respectively; p<0.01) at 2 weeks were significantly reduced from baseline. In the saline group, all the clinical parameters were reduced but there was no statistical significance. The saline may be attributed to the influence of prophylaxis at baseline. Conclusions: The present study demonstrated the beneficial clinical effects of chelating and deproteinizing agent containing dental conditioning gel to decrease peri-implant mucosa inflammation equivalent to chlorhexidine. This dental conditioning gel might be useful for alleviation of peri-implant mucosa inflammation.

Key Words: Dental implants;peri-implantitis;chelating agent;chlorhexidine;