Antimicrobial choice of severe endodontic infection

Cho,  Ju-Yeon; Ha,  Jung-Hong; Jin,  Myoung-Uk; Kim,  Young-Kyung; Kim,  Sung-Kyo

J Korean Dent Assoc > Volume 52(7); 2014 > Article

The Journal of The Korean Dental Association 2014;52(7):425-431.
Published online July 31, 2014.

심한 근관 감염에서의 항생제 선택

조주연¹, 하정홍², 진명욱³, 김영경⁴, 김성교⁵

^¹경북대학교 치의학전문대학원 치과보존학교실
^²경북대학교 치의학전문대학원 치과보존학교실
^³경북대학교 치의학전문대학원 치과보존학교실
^⁴경북대학교 치의학전문대학원 치과보존학교실
^⁵경북대학교 치의학전문대학원 치과보존학교실

Antimicrobial choice of severe endodontic infection

Ju-Yeon Cho¹, Jung-Hong Ha², Myoung-Uk Jin³, Young-Kyung Kim⁴, Sung-Kyo Kim⁵

¹Department of Conservative Dentistry, Kyungpook National University,
²Department of Conservative Dentistry, Kyungpook National University,
³Department of Conservative Dentistry, Kyungpook National University,
⁴Department of Conservative Dentistry, Kyungpook National University,
⁵Department of Conservative Dentistry, Kyungpook National University,

Abstract

Objectives
: The purpose of our study was to evaluate penicillin as a still drug of choice for severe endodontic infection, by analyzing the antimicrobial susceptibilities from endodontic infections with swelling to figure out appropriate antibiotics as empirical treatment. Materials and methods : This study involved 18 patients who attended for emergency treatment because of facial or periapical swelling associated with root canal infections. Identification and antimicrobial susceptibility test of each pathogen were performed by Vitek2 Systems (bioMacuteerieux, Marcy l'Etoile, France). Results : The most frequent bacteria was Streptococcus spp.(77%), and the resistance against penicillin was 35% in overall patients, followed by clindamycin and erythromycin (17%), which was much higher than previous studies. Conclusions : In our study, the higher resistance made penicillin alone not to be chosen as the first antibiotic drug for severe endodontic infections. Combinations with other drug, penicillin with wider spectrum of activity, or changing to other antibiotics was considered while remembering the increased risk of resistant microorganism.

Key Words: penicillin;antimicrobial;endodontic;infection;susceptibility;