Considerations during dental implant treatment for patients under bisphosphonate therapy

Park,  Won-Se; Chung,  Won-Yoon; Kim,  Hyung-Jun; Kim,  Kee-Deog

J Korean Dent Assoc > Volume 49(7); 2011 > Article

The Journal of The Korean Dental Association 2011;49(7):389-397.
Published online July 31, 2011.

Bisphosphonate를 복용하는 환자에게 임프란트 치료시 고려사항

박원서¹, 정원윤², 김형준³, 김기덕⁴

^¹연세대학교 치과대학 통합진료학과
^²연세대학교 치과대학 구강생물학교실
^³연세대학교 치과대학 구강악안면외과학교실
^⁴연세대학교 치과대학 통합진료학과

Considerations during dental implant treatment for patients under bisphosphonate therapy

Won-Se Park¹, Won-Yoon Chung², Hyung-Jun Kim³, Kee-Deog Kim⁴

¹Department of advanced general dentistry, College of dentistry, Yonsei University
²Department of oral biology, College of dentistry, Yonsei University
³Department of oral and maxillofacial sugery, College of dentistry, Yonsei University
⁴Department of advanced general dentistry, College of dentistry, Yonsei University

Abstract

Bisphosphonate inhibits the function of osteoclast, so they are widely used for multiple myeloma, Paget's disease, metastatic malignant bone disease, and severe osteoporosis. This drug is very effective for preventing severe complication of osteoporosis, some unpredictable complication occurred such as esophageal malignancy, atypical fracture of femur, and osteonecrosis of the jaw. Bisphosphonate related osteonecrosis of the jaw (BRONJ) is closely related with invasive, open bone surgery like tooth extraction. BRONJ associated with dental implant is rare, however, as the use of bisphosphonate increase, BRONJ cases with dental implant are increasing. In this article, we will describe the considerations during dental implant treatment for patient under bisphosphonate therapy.

Key Words: Bisphosphonate;implant;dental considerations;