Bisphosphonate related osteonecrosis of jaw

Hwang,  Kyung-Gyun

J Korean Dent Assoc > Volume 49(7); 2011 > Article

The Journal of The Korean Dental Association 2011;49(7):372-377.
Published online July 31, 2011.

비스포스포네이트(Bisphosphonate)를 복용하는 환자에서 발생하는 골괴사증

황경균

한양대학교 의과대학 치과학교실 구강악안면외과

Bisphosphonate related osteonecrosis of jaw

Kyung-Gyun Hwang

Oral & Maxillofacial Surgery, Department of Dentistry, Collage of Medicine, Hanyang University

Abstract

Bisphosphonates are widely used in the management of osteoporosis patients. Many reports and clinical studies have published a relationship between necrotic bone lesions localized to the jaw and the use of chronic bisphosphonate therapy. This osteonecrosis named bisphosphonate-related osteonecrosis of the jaw(BRONJ). This article described the mechanism, chemical structure, indication, risk factor of the bisphosphonate.

Key Words: Bisphosphonate;osteonecrosis;jaw;