| 중등도 치주질환에 대한 Vitamin C, Vitamin E, lysozyme, carbazochrome (이가탄(R)) 복합제제의 임상 효과 |
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장윤영1, 장용주2, 정임희3, 엄유정4, 정의원5, 김창성6, 김백일7, 최성호8 |
1연세대학교 치과대학 치주과학교실, 치주조직재생연구소
2연세대학교 치과대학 치주과학교실, 치주조직재생연구소
3연세대학교 치과대학 치주과학교실, 치주조직재생연구소
4연세대학교 치과대학 치주과학교실, 치주조직재생연구소
5연세대학교 치과대학 치주과학교실, 치주조직재생연구소
6연세대학교 치과대학 치주과학교실, 치주조직재생연구소
7연세대학교 치과대학 예방치과학교실
8연세대학교 치과대학 치주과학교실, 치주조직재생연구소 |
| Clinical effect of Vitamin C, Vitamin E, lysozyme, carbazochrome complex medicine(IGATAN(R)) in periodontal disease : Double blind, randomized control study |
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Yun-Young Chang1, Yong-Ju Jang2, Im-Hee Jung3, Yoo-Jung Um4, Ui-Won Jung5, Chang-Sung Kim6, Baek-Il Kim7, Seong-Ho Choi8 |
1Department of Periodontology, Research Institute for Periodontal Regeneration, College of Dentistry, Yonsei University
2Department of Periodontology, Research Institute for Periodontal Regeneration, College of Dentistry, Yonsei University
3Department of Periodontology, Research Institute for Periodontal Regeneration, College of Dentistry, Yonsei University
4Department of Periodontology, Research Institute for Periodontal Regeneration, College of Dentistry, Yonsei University
5Department of Periodontology, Research Institute for Periodontal Regeneration, College of Dentistry, Yonsei University
6Department of Periodontology, Research Institute for Periodontal Regeneration, College of Dentistry, Yonsei University
7Department of preventive dentistry and public oral health College of dentistry, Yonsei university
8Department of Periodontology, Research Institute for Periodontal Regeneration, College of Dentistry, Yonsei University |
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| Abstract |
Purpose
: The purpose of this study was to evaluate the clinical effect of Vitamin C, Vitamin E, lysozyme, carbazochrome complex medicine(IGATAN(R)) for periodontal disease. Material and Methods : The study was performed by double blinded, ramdomized method. Forty two subjects diagnosed as chronic incipient or moderate periodontitis at department of periodontology, Yonsei Dental Hospital were included in the study. This study was approved by Institutional Review Board, Yonsei University Hospital. All subjects received scaling at their first examination and second examination was scheduled after 2 weeks. At second examination, periodontal parameters such as plaque index(PI), gingival index(GI), probing depth(PD), bleeding on probing(BOP), gingival recession(GR) and clinical attachment level(CAL) were recorded(Baseline) with prescription of Vitamin C, Vitamin E, lysozyme, carbazochrome complex(IGATAN(R)) (Experimental group 23 subjects) or placebo medicine(Control group; 19 subjects). The subjects were recalled after 4 weeks for periodontal parameters measurement. Results : In the experimental groups, PI, GI, CAL and BOP scores were significantly reduced at 4 weeks compared to baseline. A statistically significant decrease in or and BOP scores were observed in the experimental group compared to the control group. Conclusion : It can be concluded that Vitamin C, Vitamin E, lysozyme, carbazochrome complex medicine(IGATAN(R)) have an effect in reducing gingival bleeding and improving periodontal inflammatory condition inchronic incipient- moderate periodontitis. |
| Key Words:
Vitamin C;Vitamin E;lysozyme;carbazochrome; |
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