Cortisone 및 Calcium이 국소마취약의 Acetylcholine 근련축억제효과에 미치는 영향 |
배유홍1, 함종대2, 이상신3 |
1서울대학교 치과대학 2서울대학교 치과대학 3서울대학교 치과대학 |
Yu-Hong Baei1, Jhong-Dai Hahm2, Sang-Sin Lee3 |
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Abstract |
The authors have investigated the roles of cortisone and calcium on the depressive effects of local anesthetics on the acetylcholine-induced skeletal muscle contraction in frog.
The results are as follows.
1. Tetracaine, cocaine, lidocaine and procaine decreased the acetylcholine-induced skeletal muscle contraction.
2. Cortisone increased the depressive effects of local anesthetics on the acetyl-choline-induced skeletal muscle contraction.
3. There was a tendency that in high calcium concentration, the depressive effects of cocaine and lidocaine on acetylcholine-induced skeletal muscle contraction were increased. |
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