| Isoproterenol이 백서구강점막의 비만세포에 미치는 영향 |
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고재승1, 송완영2 |
1서울대학교 치과대학 구강해부학교실
2서울대학교 치과대학 구강해부학교실 |
| Effects of Isoproterenol on the Mast Cells in The Oral Mucosa of Albino Rats. |
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Jae-Seoung Ko1, Wan-Young Song2 |
1Dept. of Oral Anatomy, College of Dentistry, S.N.U.
2Dept. of Oral Anatomy, College of Dentistry, S.N.U. |
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| Abstract |
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The effects of isoproterenol, a sympathomimetic amine, on the mast cells in the oral mucosa were cytochemically studied in twenty four healthy male albino rats weighing approximately 100gm. seven groups of three each were injected intraperitoneally, as a single dose of 8mg/100gm. body wt., (dissolved in 0.9% saline 0.2㎖). Each groups were sacrificed following ether anesthesia at he time indicated, 1. 2. 3. 5. 7. 10. 14days after only a single injection. One normal group is not administered with any substances. The sections of oral mucosa were stained with 0.005% toluidine blue (Mowry's method) and alcian blue (pH 2.5). We found that isoproterenol made an initial decrease in the metachromasia and alcian blue affinity, and the number of mast cell, followed by an subsequent return to normal. |
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